Desmethyl nevanimibe

• UNSPSC Description:

  Desmethyl nevanimibe (Compound 5) is the demethyl precursor of the sterol O-acyltransferase 1 (SOAT1) inhibitor Nevanimibe (PD-132301)[1].

• Target Antigen:

  Drug Intermediate

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/desmethyl-nevanimibe.html

• Smiles:

  O=C(NCC1(CCCC1)C2=CC=C(NC)C=C2)NC3=C(C(C)C)C=CC=C3C(C)C

• Molecular Weight:

  407.59

• References & Citations:

  [1]Hill JR, et al., Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents. ACS Med Chem Lett. 2020 Apr 30;11(6):1299-1304.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2419904-59-7