Desmethyl nevanimibe

• Description :

  Desmethyl nevanimibe (Compound 5) is the demethyl precursor of the sterol O-acyltransferase 1 (SOAT1) inhibitor Nevanimibe (PD-132301) [1].

• UNSPSC :

  12352005

• Target :

  Drug Intermediate

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/desmethyl-nevanimibe.html

• Purity :

  98.40

• Solubility :

  DMSO : ≥ 50 mg/mL

• Smiles :

  O=C(NCC1(CCCC1)C2=CC=C(NC)C=C2)NC3=C(C(C)C)C=CC=C3C(C)C

• Molecular Formula :

  C26H37N3O

• Molecular Weight :

  407.59

• References & Citations :

  [1]Hill JR, et al., Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents. ACS Med Chem Lett. 2020 Apr 30;11 (6) :1299-1304.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2419904-59-7]