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Desmethyl nevanimibe

CAT: 0804-HY-160804-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-160804-01Size: 5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Desmethyl nevanimibe (Compound 5) is the demethyl precursor of the sterol O-acyltransferase 1 (SOAT1) inhibitor Nevanimibe (PD-132301) [1].
CAS Number
[2419904-59-7]
UNSPSC
12352005
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/desmethyl-nevanimibe.html
Purity
98.40
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(NCC1(CCCC1)C2=CC=C(NC)C=C2)NC3=C(C(C)C)C=CC=C3C(C)C
Molecular Formula
C26H37N3O
Molecular Weight
407.59
References & Citations
[1]Hill JR, et al., Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents. ACS Med Chem Lett. 2020 Apr 30;11 (6) :1299-1304.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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