U-51605

CAT: 0804-HY-129199-01Size: 100 µgDry Ice: NoHazardous: No
CAT#:0804-HY-129199-01Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
U-51605 is a platelet aggregation inhibitor and inhibits thromboxane synthesis. U-51605 is also a prostaglandin I2 synthase inhibitor and can inhibit the retinal vasodilation response induced by NO donors (such as NOR3) [1][2].
CAS Number
[64192-56-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/u-51605.html
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C\C[C@@H]1[C@H]([C@@]2([H])C[C@]1([H])N=N2)/C=C/CCCCCC)=O
Molecular Formula
C20H32N2O2
Molecular Weight
332.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Needleman P, Bryan B, Wyche A, et al. Thromboxane synthetase inhibitors as pharmacological tools: differential biochemical and biological effects on platelet suspensions[J]. Prostaglandins, 1977, 14 (5) : 897-907.|[2]Mori A, Namekawa R, Hasebe M, et al. Involvement of prostaglandin I2 in nitric oxide-induced vasodilation of retinal arterioles in rats[J]. European Journal of Pharmacology, 2015, 764: 249-255.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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