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Kuwanon U

CAT: 0804-HY-N12581-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N12581-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kuwanon U is a potent cholinesterase inhibitor with IC50s of 19.69, 10.11 µM and Kis of 6.48, 9.59 µM for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), respectively. Kuwanon U has the potential for the research of Alzheimer’s disease (AD) [1].
CAS Number
123702-95-4
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kuwanon-u.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(C/C=C(C)/CC/C=C(C)\C)=C(C=C3O)OC)C1
Molecular Formula
C26H30O6
Molecular Weight
438.51
References & Citations
[1]Kim JY, et al. Isolation of cholinesterase-inhibiting flavonoids from Morus lhou. J Agric Food Chem. 2011 May 11;59 (9) :4589-96.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE; BChE

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