Products for Research Use Only
RegisterLogin

DS-1558

CAT: 0804-HY-12976Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12976Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DS-1558 is an orally active small molecule G protein-coupled receptor 40 agonist. DS-1558 not only increases the glucose-stimulated insulin secretion by glucagon like peptide-1 (GLP-1) but also potentiated the maximum insulinogenic effects of GLP-1 after an intravenous glucose injection in normal Sprague Dawley rats. DS-1558 is promising for research of type 2 diabetes[1].
CAS Number
1202575-67-4
UNSPSC
12352005
Target
G Protein-coupled Receptor Kinase (GRK)
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ds-1558.html
Smiles
FC(F)(C1=C2C([C@@H](CC2)OC3=CC=C(C=C3)[C@@H](OCC)CC(O)=O)=CC=C1)F
Molecular Formula
C21H21F3O4
Molecular Weight
394.38
References & Citations
[1]Nakashima R, et al. Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists. Eur J Pharmacol. 2014 Aug 15;737:194-201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-144390-01(S) -S007-1558
HY-124131-01DS-437
HY-131182-01DS-1971a
HY-P991365DS-1501
HY-116880DS-2969b
HY-114217DS-003
HY-144401-01DS-3801b
HY-152241-01DS-9300
HY-P991577-01DS-8895
HY-163839DS-1093a

Alternative Products

CatalogName
MBS5813790DS-1558
C18240DS-1001b (DS 1001)
GTR17698237Desmoplakin (aa 1546-1558) Antibody
STJ72284Anti-Desmoplakin (aa 1546-1558) antibody
BA7852-50DS-1001b
BA4837-50DS-437
BA4774-1DS-9300
BD181252-01DS 16570511
T9901A-1690-01DS-1501
T89077-01DS-1093a

Popular Products