(RXR)4XB

• UNSPSC Description:

  (RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models[1].

• Target Antigen:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/rxr-4xb.html

• Smiles:

  N=C(N)NCCC[C@H](N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(NCCCCCC(NCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1904.37

• References & Citations:

  [1]Howard JJ, et al., Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e01938-16.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  879010-15-8