Simazine-d10

• Description :

  Simazine-d10 is the deuterium labeled Simazine (HY-B2046) . Simazine is a triazine herbicide. Simazine is widely used in agriculture, potted plant and tree production. In addition, Simazine can induce the apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice[1][2].

• CAS Number :

  [220621-39-6]

• UNSPSC :

  12352005

• Hazard Statement :

  H351-H410

• Target :

  Apoptosis; Bcl-2 Family; Caspase; Herbicide; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research :

  Inflammation/Immunology

• Solubility :

  10 mM in DMSO

• Smiles :

  [2H]C([2H])([2H])C(NC1=NC(Cl)=NC(NC([2H])([2H])C([2H])([2H])[2H])=N1)([2H])[2H]

• Molecular Formula :

  C7H2D10ClN5

• Molecular Weight :

  211.72

• Precautions :

  P273-P280-P391-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Morten T Strandberg, et al. Field Effects of Simazine at Lower Trophic Levels--A Review. ci Total Environ. 2002 Sep 16;296 (1-3) :117-37.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported