Simazine

CAT: 0804-HY-B2046-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B2046-01Size:50 mg
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Description
Simazine is a triazine herbicide. Simazine is widely used in agriculture, potted plant and tree production. In addition, Simazine can induce the apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice[1][2][3].
CAS Number
[122-34-9]
UNSPSC
12352005
Hazard Statement
H302, H351, H400, H410
Target
Apoptosis; Bcl-2 Family; Caspase; Herbicide; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/simazine.html
Purity
99.72
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCNC1=NC(Cl)=NC(NCC)=N1
Molecular Formula
C7H12ClN5
Molecular Weight
201.66
Precautions
H302, H351, H400, H410
References & Citations
[1]Morten T Strandberg, et al. Field Effects of Simazine at Lower Trophic Levels--A Review. ci Total Environ. 2002 Sep 16;296 (1-3) :117-37.|[2]Ren R, et al. Oral exposure to the herbicide simazine induces mouse spleen immunotoxicity and immune cell apoptosis. Toxicol Pathol. 2013 Jan;41 (1) :63-72.|[3]Shang JZ, et al. Simazine perturbs the maturational competency of mouse oocyte through inducing oxidative stress and DNA damage. Ecotoxicol Environ Saf. 2022 Jan 15;230:113105.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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