Thalidomide-NH-C-C6H10-C-acid

Thalidomide-NH-C-C6H10-C-acid

• UNSPSC Description: Thalidomide-NH-C-C6H10-C-acid is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT (HY-168131)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-c-c6h10-c-acid.html
• Smiles: OC(CC1CCC(CC1)CNC2=C(C3=CC=C2)C(N(C3=O)C4C(NC(CC4)=O)=O)=O)=O
• Molecular Weight: 427.45
• References & Citations: [1]Fu M, et, al. Chemically induced degradation of PRC2 complex by EZH2-Targeted PROTACs via a Ubiquitin-Proteasome pathway. Bioorg Med Chem Lett. 2024 Nov 15:113:129968.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported