GSK1521498 (free base)
CAT:
804-HY-115066-01
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GSK1521498 (free base)
- CAS Number: 1007573-18-3
- UNSPSC Description: GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base has the potential for disorders of compulsive consumption of food, alcohol, and agents[1].
- Target Antigen: Opioid Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/gsk1521498-free-base.html
- Purity: 98.55
- Solubility: DMSO : 11.36 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: FC1=C(CNC2CC3=C(C=CC=C3)C2)C(F)=CC(C4=CC=CC(C5=NC=NN5)=C4)=C1
- Molecular Weight: 402.44
- References & Citations: [1]Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 2