7030B-C5

• Description :

  7030B-C5 is a PCSK9 inhibitor (IC50=1.61 μM) . 7030B-C5 can significantly reduce plasma cholesterol and triglyceride (TG) levels in vivo and slow the progression of atherosclerosis. 7030B-C5 can be used in the study of cardiovascular diseases[1].

• UNSPSC :

  12352005

• Target :

  PCSK9

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/7030b-c5.html

• Purity :

  99.78

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1C2=C(N=C(NCCO)N2CC3=CC=CC(OC)=C3)N(C)C(N1C)=O

• Molecular Formula :

  C17H21N5O4

• Molecular Weight :

  359.38

• References & Citations :

  [1]Xuhui Bao, et al. "Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) : from bench to bedside." Signal Transduction and Targeted Therapy 9.1 (2024) : 13.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [370871-42-4]