C5 Lenalidomide

CAT: 0804-HY-132248-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-132248-01Size:50 mg
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Description
C5 Lenalidomide (Lenalidomide 5'-amine) (Compound 8a) is a thalidomide analog and is a potent inhibitor of TNF-α production (IC50 = 100 μM in LPS stimulated human PBMC and IC50 = 480 nM in whole blood) [1].
CAS Number
[191732-70-4]
Product Name Alternative
Lenalidomide 5'-amine
UNSPSC
12352005
Hazard Statement
H361, H373
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c5-lenalidomide.html
Purity
99.62
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C(N(CC1=C2C=CC(N)=C1)C2=O)CC3)NC3=O
Molecular Formula
C13H13N3O3
Molecular Weight
259.26
Precautions
H361, H373
References & Citations
[1]G W Muller, et al. Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg Med Chem Lett. 1999 Jun 7;9 (11) :1625-30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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