CM-H2DCFDA

• Description:

  CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940) . CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm) . CM-H2DCFDA is light-sensitive[1].

• UNSPSC:

  12171500

• Target:

  Reactive Oxygen Species (ROS)

• Type:

  Dye Reagents

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/cm-h2dcfda.html

• Purity:

  92.0

• Solubility:

  DMSO : 3 mg/mL (ultrasonic; warming)

• Smiles:

  CC (OC1=C (Cl) C=C2C (C3=C (C=CC (CCl) =C3) C (OC (C) =O) =O) C4=CC (Cl) =C (OC (C) =O) C=C4OC2=C1) =O.CC (OC5=C (Cl) C=C6C (C7=C (C=C (CCl) C=C7) C (OC (C) =O) =O) C8=CC (Cl) =C (OC (C) =O) C=C8OC6=C5) =O

• Molecular Formula:

  C27H19Cl3O8

• Molecular Weight:

  577.79

• References & Citations:

  [1]Oparka M, et al. Quantifying ROS levels using CM-H2DCFDA and HyPer. Methods. 2016 Oct 15;109:3-11.|[2]Kolarova H, et al. Production of reactive oxygen species after photodynamic therapy by porphyrin sensitizers. Gen Physiol Biophys. 2008 Jun;27 (2) :101-5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  850013-49-9