(±)-PPCC

(±)-PPCC

• CAS Number: 932736-90-8
• UNSPSC Description: (±)-PPCC is a sigma-1 agonist that mainly interacts with sigma-1 receptors with Ki of 1.5 nM. (±)-PPCC has effective anti-amnesia effects in rats with mild or severe cognitive impairment, and can improve the cognitive abilities of rats[1].
• Target Antigen: Sigma Receptor
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/racemic-ppcc.html
• Smiles: COC([C@]1(C2=CC=C(C=C2)C)[C@@H](C1)CN3CCC(CC3)(C4=CC=CC=C4)O)=O
• Molecular Weight: 379.49
• References & Citations: [1]Antonini V, et al. Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J Neurochem. 2009 May;109(3):744-54.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported