(±) -PPCC

• Description :

  (±) -PPCC is a sigma-1 agonist that mainly interacts with sigma-1 receptors with Ki of 1.5 nM. (±) -PPCC has effective anti-amnesia effects in rats with mild or severe cognitive impairment, and can improve the cognitive abilities of rats[1].

• UNSPSC :

  12352005

• Target :

  Sigma Receptor

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/racemic-ppcc.html

• Smiles :

  COC([C@]1(C2=CC=C(C=C2)C)[C@@H](C1)CN3CCC(CC3)(C4=CC=CC=C4)O)=O

• Molecular Formula :

  C24H29NO3

• Molecular Weight :

  379.49

• References & Citations :

  [1]Antonini V, et al. Anti-amnesic properties of (+/-) -PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J Neurochem. 2009 May;109 (3) :744-54.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [932736-90-8]