PPC-NHS ester

• UNSPSC Description:

  PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ppc-nhs-ester.html

• Purity:

  98.32

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(SSC1=NC=CC=C1)CC(ON2C(CCC2=O)=O)=O

• Molecular Weight:

  326.399

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  107348-47-0