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(E/Z) -DMU2139

CAT: 0804-HY-126308-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126308-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -DMU2139 (Compound 180) is the E/Z isomer of DMU2139. (E/Z) -DMU2139 is a potent and specific CYP1B1 inhibitor (IC50: 4 nM).
CAS Number
104890-70-2
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-dmu2139.html
Smiles
O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3
Molecular Formula
C19H15NO2
Molecular Weight
289.33
References & Citations
[1]Wang Y, et al. Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification. Eur J Med Chem. 2020 May 1;193:112235.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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