(E/Z) -DMU2139

• Description :

  (E/Z) -DMU2139 (Compound 180) is the E/Z isomer of DMU2139 (HY-101285) . (E/Z) -DMU2139 is a potent and specific CYP1B1 inhibitor (IC50: 4 nM) [1].

• UNSPSC :

  12352005

• Target :

  Cytochrome P450

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/e-z-dmu2139.html

• Smiles :

  O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3

• Molecular Formula :

  C19H15NO2

• Molecular Weight :

  289.33

• References & Citations :

  [1]Wang Y, et al. Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification. Eur J Med Chem. 2020 May 1;193:112235.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [104890-70-2]