(E/Z)-DMU2139

• UNSPSC Description:

  (E/Z)-DMU2139 (Compound 180) is the E/Z isomer of DMU2139 (HY-101285). (E/Z)-DMU2139 is a potent and specific CYP1B1 inhibitor (IC50: 4 nM)[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-z-dmu2139.html

• Smiles:

  O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3

• Molecular Weight:

  289.33

• References & Citations:

  [1]Wang Y, et al. Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification. Eur J Med Chem. 2020 May 1;193:112235.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  104890-70-2