DMU2139 (Standard)

CAT: 0804-HY-101285RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-101285RSize:1 Each
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Description
DMU2139 (Standard) is the analytical standard of DMU2139 (HY-101285) . This product is intended for research and analytical applications. DMU2139 is a potent and specific CYP1B1 inhibitor, with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively.
CAS Number
[1821143-80-9]
Target
Cytochrome P450; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3
Molecular Formula
C19H15NO2
Molecular Weight
289.33
References & Citations
[1]Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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