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MK-1421

CAT: 0804-HY-12819Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12819Size:1 Each
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Description
MK-1421 is a potent and selective sstr3 antagonist. MK-1421 regulates insulin secretion by binding to the sstr3. MK-1421 can be used in the research of type 2 diabetes[1].
CAS Number
1235995-16-0
UNSPSC
12352005
Target
Somatostatin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mk-1421.html
Smiles
FC(C=C1)=CN=C1C2=CNC([C@@H]3N[C@@](C4=CN(CC)N=C4)(C5=NN(C)C(O5)=O)C6=C(C(C=CC=C7)=C7N6)C3)=N2
Molecular Formula
C27H24FN9O2
Molecular Weight
525.54
References & Citations
[1]Shah S K, et al. Discovery of MK-1421, a potent, selective sstr3 antagonist, as a development candidate for type 2 diabetes[J]. ACS Medicinal Chemistry Letters, 2015, 6 (5) : 513-517.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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