Aminoacyl tRNA synthetase-IN-1

• UNSPSC Description:

  Aminoacyl tRNA synthetase-IN-1 is a bacterial aminoacyl tRNA synthetase (aaRS) inhibitor.

• Target Antigen:

  Aminoacyl-tRNA Synthetase; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Aminoacyl_tRNA_synthetase-IN-1.html

• Purity:

  99.80

• Solubility:

  DMSO : 65 mg/mL (ultrasonic)

• Smiles:

  O[C@@H]1[C@@H](COS(=O)(NC([C@H]([C@@H](C)CC)N)=O)=O)O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@@H]1O

• Molecular Weight:

  459.48

• References & Citations:

  [1]Vondenhoff GH, et al. Microcin C and albomycin analogues with aryl-tetrazole substituents as nucleobase isosters areselective inhibitors of bacterial aminoacyl tRNA synthetases but lack efficient uptake. Chembiochem. 2012 Sep 3;13(13):1959-69.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  219931-45-0