Ranitidine (hydrochloride)
CAT:
804-HY-B0281A-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Ranitidine (hydrochloride)
- CAS Number: 66357-59-3
- UNSPSC Description: Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine hydrochloride is a weak inhibitor of CYP2C19 and CYP2C9[1][2].
- Target Antigen: Bacterial; Cytochrome P450; Histamine Receptor
- Type: Reference compound
- Related Pathways: Anti-infection;GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Infection; Endocrinology; Metabolic Disease; Cancer; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/ranitidine-hydrochloride.html
- Purity: 99.88
- Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
- Smiles: CN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O.Cl
- Molecular Weight: 350.86
- References & Citations: [1]Herling, A.W., et al., Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Agents Actions, 1987. 20(1-2): p. 35-9.|[2]Leucuta, A., et al., A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact, 2004. 20(4): p. 273-81.|[3] Antonio Francesco Ciccaglione, et al. Pylera® plus ranitidine vs Pylera® plus esomeprazole in first-line treatment of Helicobacter pylori infection: Two pilot studies. Helicobacter. 2019 Oct;24(5):e12606.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched