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Polθ-IN-6

CAT: 0804-HY-169285Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169285Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polθ-IN-6 (Compound 89) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-6 has antitumor activity[1].
CAS Number
3058496-94-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/polθ-in-6.html
Smiles
O=C(C1=CN=C(C)C=C1C2=C(OC)C=CC=C2)NC3=NC4=C(S3)C=C(C5OCCC5)C=C4
Molecular Formula
C25H23N3O3S
Molecular Weight
445.53
References & Citations
[1]Michael H Reutershan, et al. Biaryl derivatives and related uses. WO2024211834A1.2024-10-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported