Products for Research Use Only

Polθ-IN-8

CAT: 0931-T207723-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207723-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3056743-98-4
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.
Smiles
O=C(NC1=NC=2C=NC(=NC2S1)NCC(O)(C)C)C=3C=NC(=CC3C4=CC(Cl)=NC=C4OC)C
Molecular Formula
C22H22ClN7O3S
Molecular Weight
499.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C