Polθ-IN-7

CAT: 0804-HY-153755Size: 1 EachDry Ice: NoHazardous: No

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Description

Polθ-IN-7 (example 12) is a DNA polymerase theta (Polθ) inhibitor with a Ki of 1.27 nM[1].

CAS Number

2923356-52-7

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1[C@@]2([H])N(C3=CC(C(F)(F)F)=CC(C)=N3)C(C[C@]2([H])CN(C4=C(C)C=CC=C4N1C)CCN5CCN(CC5)C)=O

Molecular Formula

C28H35F3N6O2

Molecular Weight

544.61

References & Citations

[1]Owen Davis, et al. Heterocyclic compounds for use in the treatment of cancer. WO2023067355A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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