CGP 28014

CAT: 0804-HY-19061Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19061Size:1 Each
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Description
CGP 28014 is a catechol-O-methyltransferase inhibitor. CGP 28014 can lower HVA levels and increase DOPAC levels in the striatum of rats, making it useful for research on Parkinson's disease[1].
CAS Number
[111757-17-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgp-28014.html
Smiles
O=C1C=CC=C(N1)/N=C/N(CCC)CCC
Molecular Formula
C12H19N3O
Molecular Weight
221.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Waldmeier PC, et al. CGP 28014, a new inhibitor of cerebral catechol-O-methylation with a non-catechol structure. Naunyn Schmiedebergs Arch Pharmacol. 1990 Sep;342 (3) :305-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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