SAHA-BPyne

CAT: 0804-HY-126943-01Size: 100 µgDry Ice: NoHazardous: No
CAT#:0804-HY-126943-01Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM[1].
CAS Number
[930772-88-6]
UNSPSC
12352005
Hazard Statement
H225-H301+H311+H331-H370
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/saha-bpyne.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)CCCCCCC(NC1=CC=C(C(C2=CC=C(NC(CCCC#C)=O)C=C2)=O)C=C1)=O
Molecular Formula
C27H31N3O5
Molecular Weight
477.55
Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Salisbury CM, et al., Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes. J Am Chem Soc. 2008 Feb 20;130 (7) :2184-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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