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Coumarin-SAHA

CAT: 0804-HY-126829Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126829Size:1 mg
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Description
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].
CAS Number
1260635-77-5
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/coumarin-saha.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)CCCCCCC(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)=O
Molecular Formula
C18H22N2O5
Molecular Weight
346.38
References & Citations
[1]Raushan K Singh, et al. Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors. Anal Biochem
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC8

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