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4-Iodo-SAHA

CAT: 0804-HY-124007Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124007Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Iodo-SAHA (1k) is an orally active class I and class II histone deacetylase (HDAC) inhibitor with EC50s of 1.1, 0.95, 0.12, 0.24, 0.85 and 1.3 μM for Skbr3, HT29, U937, JA16 and HL60 cell lines, respectively. 4-Iodo-SAHA (1k) can be used for the research of cancer[1].
CAS Number
1219807-87-0
Product Name Alternative
ISAHA
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-iodo-saha.html
Solubility
10 mM in DMSO
Smiles
IC1=CC=C(C=C1)NC(CCCCCCC(NO)=O)=O
Molecular Formula
C14H19IN2O3
Molecular Weight
390.22
References & Citations
[1]Salmi-Smail C, et al. Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity. J Med Chem. 2010 Apr 22;53 (8) :3038-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported