Products for Research Use Only
RegisterLogin

COP1-ATGL modulator 1

CAT: 0804-HY-157416-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-157416-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
COP1-ATGL modulator 1 (86) is an orally active modulator for COP1-ATGL axis. COP1-ATGL modulator 1 (86) could increase ATGL protein expression, reduce ATGL ubiquitination and COP1 autoubiquitination, and diminish lipid accumulation in hepatocytes in the nanomolar range[1].
CAS Number
2946701-09-1
UNSPSC
12352005
Target
ATGL; E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cop1-atgl-modulator-1.html
Concentration
10mM
Purity
99.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C(C2=CC(NC(NC3=CC(C(C)=O)=CC=C3)=O)=CC=C2N1CCN4CCCCC4)=O)CCOC
Molecular Formula
C27H33N5O5
Molecular Weight
507.58
References & Citations
[1]Dipayan Sarkar, et al. Discovery and Development of Quinazolinones and Quinazolinediones for Ameliorating Nonalcoholic Fatty Liver Disease (NAFLD) by Modulating COP1-ATGL Axis. J Med Chem. 2023 Dec 28;66 (24) :16728-16761.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-164311GPR17 modulator-1
HY-111996-01Kv3 modulator 1
HY-148617ALDH2 modulator 1
HY-153690Progranulin modulator-1
HY-135671AhR modulator-1
HY-148878Ras modulator-1
HY-175597ClpP modulator-1
HY-169913ERAP1 modulator-1
HY-159742-01GP130 modulator-1
HY-169288α-Synuclein modulator 1

Alternative Products

CatalogName
GTR19235635-01COP1-ATGL modulator 1
E8RT1058ATGL
311775-01COP1
10R-1132ATGL antibody
507064ATGL discontinued
45-306PATGL Peptide
342660-01COP1 discontinued

Popular Products