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Progesterone-d9

CAT: 0804-HY-N0437S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0437S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
CAS Number
15775-74-3
Product Name Alternative
Pregn-4-ene-3,20-dione-d9
UNSPSC
12352211
Hazard Statement
H225, H302+H332, H319
Target
Endogenous Metabolite; Progesterone Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cardiovascular Disease; Cancer
Purity
99.97
Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
Smiles
C[C@]12[C@]([H])([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])=O)[2H])[2H])[H])CC[C@@]1(C(C([2H])([2H])[2H])=O)[2H]
Molecular Formula
C21H21D9O2
Molecular Weight
323.52
Precautions
H225, H302+H332, H319
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.|[3]Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217 (3) :369-78.|[4]Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4 (2) :144-50.|[5]Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148 (11) :5433-41. Epub 2007 Aug 9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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