Progesterone-d9

• Description:

  Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

• Product Name Alternative:

  Pregn-4-ene-3,20-dione-d9

• UNSPSC:

  12352211

• Hazard Statement:

  H225, H302+H332, H319

• Target:

  Endogenous Metabolite; Progesterone Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cardiovascular Disease; Cancer

• Purity:

  99.97

• Solubility:

  DMSO : 50 mg/mL (ultrasonic; warming)

• Smiles:

  C[C@]12[C@]([H])([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])=O)[2H])[2H])[H])CC[C@@]1(C(C([2H])([2H])[2H])=O)[2H]

• Molecular Formula:

  C21H21D9O2

• Molecular Weight:

  323.52

• Precautions:

  H225, H302+H332, H319

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.|[3]Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217 (3) :369-78.|[4]Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4 (2) :144-50.|[5]Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148 (11) :5433-41. Epub 2007 Aug 9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  15775-74-3