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SESN3 rabbit pAb

CAT: 0855-ES13146-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13146-01Size:50 µL
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Background
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Description
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
UniProt
P58005
Swiss Prot
P58005
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human SESN3 AA range: 35-85
Target
SESN3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm .
Gene ID (Human)
143686

UniProtKB · P58005

Sestrin-3

SESN3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P58005
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SESN3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.11.1.-
Processing
—
Secondary accessions
B7Z7P9, Q96AD1
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

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A5164-01SESN3 Rabbit pAb
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