Peptide 74

• Description:

  Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP) . Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

• UNSPSC:

  12352209

• Target:

  MMP

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/peptide-74.html

• Purity:

  98.50

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@@H](O)[C@H](N)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(NCC(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C62H107N23O20S2

• Molecular Weight:

  1558.79

• References & Citations:

  [1]A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52 (8) :2353-6.|[2]P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188 (1) :75-88.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [132116-39-3]