PCSK9-IN-27
CAT:
804-HY-161435
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PCSK9-IN-27
- UNSPSC Description: PCSK9-IN-27 (Compound 108) is a PCSK9 inhibitor (IC50: 3.4 nM). PCSK9-IN-27 reduces LDLR degradation and increases LDL-C uptake[1].
- Target Antigen: PCSK9
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/pcsk9-in-27.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1N(C=CC=C1Cl)C2=CN=C(N[C@@H]3C[C@@H](NC4=CN=C(C5CC5)C=N4)CC3)C=C2
- Molecular Weight: 422.91
- References & Citations: [1]Gavin Donal O’MAHONY, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2024062089A1
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported