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PCSK9-IN-15

CAT: 0804-HY-153451Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153451Size:1 Each
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Description
PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, KD [1].
CAS Number
2455423-94-4
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(CC1)O)C2=CC=C(N=C(S3)NC[C@@H](C)CNC4=NC=C(SC)C=N4)C3=C2
Molecular Formula
C22H28N6O2S2
Molecular Weight
472.63
References & Citations
[1]Serrano-Wu MH, et al. Preparation of 2-[[2-methyl-3-[[5- (methylthio) pyrimidin-2-yl]amino]propyl]amino]benzo[d]thiazoles and analogs as PCSK9 inhibitors and methods of their use. World Intellectual Property Organization, WO2020150474 A1. 2020-07-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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