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Hypericin-d2

CAT: 0804-HY-N0453S1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0453S1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hypericin-d2 is deuterium labeled Hypericin.
UNSPSC
12352005
Target
Apoptosis; Influenza Virus
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
94.68
Solubility
10 mM in DMSO|DMSO : 250mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(O)C([2H])=C(O)C3=C2C4=C(C5=C6C(O)=CC(C)=C5C7=C4C1=C(O)C=C7C)C8=C3C(O)=C([2H])C(O)=C8C6=O
Molecular Formula
C30H14D2O8
Molecular Weight
506.46
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Agostinis P et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 2002 Mar;34 (3) :221-41.|[3]Hwang MS et al. Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 2001 Jul-Aug;21 (4A) :2649-55.|[4]Lenard J et al. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses usinghypericin and rose bengal: inhibition of fusion and syncytia formation. Proc Natl Acad Sci U S A. 1993 Jan 1;90 (1) :158-62.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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