Hypericin-d2

• Description :

  Hypericin-d2 is deuterium labeled Hypericin.

• UNSPSC :

  12352005

• Target :

  Apoptosis; Influenza Virus

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection; Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  94.68

• Solubility :

  10 mM in DMSO|DMSO : 250mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C1C2=C(O)C([2H])=C(O)C3=C2C4=C(C5=C6C(O)=CC(C)=C5C7=C4C1=C(O)C=C7C)C8=C3C(O)=C([2H])C(O)=C8C6=O

• Molecular Formula :

  C30H14D2O8

• Molecular Weight :

  506.46

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Agostinis P et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 2002 Mar;34 (3) :221-41.|[3]Hwang MS et al. Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 2001 Jul-Aug;21 (4A) :2649-55.|[4]Lenard J et al. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses usinghypericin and rose bengal: inhibition of fusion and syncytia formation. Proc Natl Acad Sci U S A. 1993 Jan 1;90 (1) :158-62.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported