Hypericin-d2

• UNSPSC Description:

  Hypericin-d2 is deuterium labeled Hypericin.

• Target Antigen:

  Apoptosis; Influenza Virus

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection;Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Purity:

  94.68

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(O)C([2H])=C(O)C3=C2C4=C(C5=C6C(O)=CC(C)=C5C7=C4C1=C(O)C=C7C)C8=C3C(O)=C([2H])C(O)=C8C6=O

• Molecular Weight:

  506.46

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Agostinis P et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 2002 Mar;34(3):221-41.|[3]Hwang MS et al. Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 2001 Jul-Aug;21(4A):2649-55.|[4]Lenard J et al. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses usinghypericin and rose bengal: inhibition of fusion and syncytia formation. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):158-62.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported