Glyoxal-d2
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Glyoxal-d2
Description:
Glyoxal-d2 is the deuterium labeled Glyoxal (HY-Y0785) . Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs) . Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2].UNSPSC:
12352211Target:
Drug Metabolite; Isotope-Labeled CompoundsRelated Pathways:
Metabolic Enzyme/Protease; OthersApplications:
Metabolism-protein/nucleotide metabolismField of Research:
Metabolic DiseaseSmiles:
O=C([2H])C([2H])=OMolecular Formula:
C2D2O2Molecular Weight:
60.05References & Citations:
[1]Shangari N, O'Brien PJ. The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol. 2004 Oct 1;68 (7) :1433-42.|[2]Lange JN, et al. Glyoxal formation and its role in endogenous oxalate synthesis. Adv Urol. 2012;2012:819202.Shipping Conditions:
Room temperatureScientific Category:
Isotope-Labeled CompoundsClinical Information:
No Development ReportedCAS Number:
[16355-99-0]
