Thioredoxin Rabbit Polyclonal Antibody

Thioredoxin Rabbit Polyclonal Antibody

• Description: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
• Product Name Alternative: ADF antibody ATL-derived factor antibody SASP antibody Surface associated sulphydryl protein antibody TRN antibody TXN 1 antibody TXN antibody
• Abbreviation: Trx,ADF,SASP
• CAS Number: 9007-83-4
• Swiss Prot: P10599 Human, P10639 Mouse
• Cellular Locus: Nucleus. Cytoplasm. Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within Human Thioredoxin aa 66-105 / 105.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Hela, HepG2, A431, PC-3M, MCF-7, human liver tissue, human kidney tissue, mouse kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:100;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 12 kDa, additional band 40 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No