Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8]

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8]

• Description: Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
• Product Name Alternative: ADF antibody ATL derived factor antibody ATL-derived factor antibody DKFZp686B1993 antibody MGC61975 antibody SASP antibody Surface associated sulphydryl protein antibody Surface-associated sulphydryl protein antibody testicular tissue protein Li 199 antibody THIO_HUMAN antibody Thioredoxin antibody thioredoxin delta 3 antibody TRDX antibody TRX 1 antibody Trx antibody TRX1 antibody TXN antibody TXN delta 3 antibody TXN protein antibody zgc:92903 antibody
• Abbreviation: TRX1, Trx, ADF, SASP, TXN
• CAS Number: 9000-83-3
• Swiss Prot: P10599 Human, P10639 Mouse, P11232 Rat
• Cellular Locus: Nucleus, Cytoplasm, Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Thioredoxin aa 78-105 / 105.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: HeLa cell lysate, 293T cell lysate, Mouse kidney tissue lysate, Mouse liver tissue lysate, Mouse colon tissue lysate, Rat colon tissue lysate, rat big intestine tissue, human small intestine tissue, mouse kidney tissue, human kidney tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000-1:5,000 ;IHC-P: 1:400-1:1,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 12 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes