ABCA1 Rabbit Polyclonal Antibody

ABCA1 Rabbit Polyclonal Antibody

• Description: ABC1 (for ATP-binding cassette transporter 1) is a member of the family of ATP-binding cassette proteins which transport various molecules across biological membranes. ABC1 contains two characteristic ATP-binding domains and 12 transmembrane domains which form a channel-like structure for transport. Mutations in the ABC1 gene are implicated in Tangier disease, characterized by low serum high density lipoprotein. ABC1 is widely expressed in human tissues, with high levels of expression in liver, lung, adrenal glands, placenta and fetal tissue. ABC1 expression is induced during monocyte differentiation and upregulated in the presence of acetylated low-density lipoprotein. ABC1 may have a dual regulatory function in macrophage lipid metabolism and inflammation.
• Product Name Alternative: ABC 1 antibody ABC Transporter 1 antibody ABC-1 antibody ABC1 antibody ABCA 1 antibody ABCA1 antibody ABCA1_HUMAN antibody ATP binding Cassette 1 antibody ATP binding cassette sub family A ABC1 member 1 antibody ATP binding cassette sub family A member 1 antibody ATP binding Cassette Transporter 1 antibody ATP-binding cassette 1 antibody ATP-binding cassette sub-family A member 1 antibody ATP-binding cassette transporter 1 antibody CERP antibody Cholesterol efflux regulatory protein antibody FLJ14958 antibody HDLDT1 antibody Membrane bound antibody MGC164864 antibody MGC165011 antibody TD antibody TGD antibody
• Abbreviation: ABC-1,ATP-binding cassette 1
• CAS Number: 9007-83-4
• Swiss Prot: O95477 Human, P41233 Mouse, Q80ZB2 Rat
• Cellular Locus: Membrane
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human ABCA1 aa 21-70 / 2,261.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: Rat brain tissue lysate, Jurkat cell lysate, mouse brain tissue lysate, PC-3M, human liver tissue, human pancreas tissue, mouse prostate tissue, mouse pancreas tissue, Jurkat.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 254 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No