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PP2A (alpha+beta) Rabbit Polyclonal Antibody

CAT: 0992-R1510-31Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1510-31Size:100 µL
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Description
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A? and PP2A∫. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-α and -A-β, PP2A-B-α and -B-β, PP2A-C-α and -C-β, PP2A-B56-α and -B56-β.
CAS Number
9007-83-4
Product Name Alternative
PP2A A antibody PP2A alpha antibody PP2A B antibody PP2A beta antibody PP2A-alpha antibody PP2AA_HUMAN antibody PP2Ac antibody PP2CB antibody PPP2CA antibody PPP2CB antibody Protein phosphatase 2 catalytic subunit alpha isoform antibody Protein phosphatase 2 catalytic subunit beta isoform antibody Replication protein C antibody RP C antibody RP-C antibody Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody Serine/threonine protein phosphatase 2A catalytic subunit beta isoform antibody Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody
Abbreviation
PP2A-alpha,RP-C
Swiss Prot
P67775 Human, P63330 Mouse, P63331 Rat
Cellular Locus
Cytoplasm, Nucleus, Chromosome
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to of Human PP2A (alpha+beta) aa 260-309 / 309.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Hela, A431, HepG2, PC12, human breast carcinoma tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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