Inhibin beta A Rabbit Polyclonal Antibody

• Description:

  Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects. The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

• Product Name Alternative:

  Activin beta-A chain antibody EDF antibody Erythroid differentiation factor antibody Erythroid differentiation protein antibody Follicle stimulating hormone releasing protein antibody FRP antibody FSH releasing protein antibody INHBA antibody INHBA_HUMAN antibody Inhibin beta A chain antibody Inhibin beta A subunit antibody Inhibin, beta 1 antibody Inhibin, beta A (activin A, activin AB alpha polypeptide) antibody

• Abbreviation:

  INHBA

• Swiss Prot:

  P08476 Human, Q04998 Mouse, P18331 Rat

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within human Inhibin beta A aa 340-390 / 426.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  SW1990 cell lysate, PANC-1 cell lysate, mouse colon tissue lysate, rat liver tissue lysate, rat heart tissue lysate, SiHa, human placenta tissue, mouse placenta tissue, PANC-1.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200;FC: 1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  47 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4