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Beta TRCP Rabbit Polyclonal Antibody

CAT: 0992-HA500358Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500358Size:100 µL
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Description
F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 residue structural motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a phosphorylation-dependent manner. F-box proteins are divided into 3 classes: Fbxws containing WD40 repeats; Fbxls containing leucine-rich repeats; Fbxos containing either "other" protein–protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxw class as, in addition to an F-box, this protein contains multiple WD40 repeats. This protein is homologous to Xenopus βTrCP, yeast Met30, Neurospora Scon2 and Drosophila Slimb. In mammals, in addition to βTrCP1, a paralog protein (called βTrCP2 or FBXW11) also exists, but, so far, their functions appear redundant and indistinguishable.
CAS Number
9007-83-4
Product Name Alternative
Beta transducin repeat containing E3 ubiquitin protein ligase antibody beta TrCP1 antibody beta-transducin repeat containing antibody BETA-TRCP antibody betaTrCP antibody btrC antibody bTrCP antibody bTrCP1 antibody E3RSIkappaB antibody F box and WD repeat protein 1B antibody F box and WD repeats protein beta TrCP antibody F-box and WD repeats protein beta-TrCP antibody F-box/WD repeat protein 1A antibody F-box/WD repeat-containing protein 1A antibody FBW1A antibody FBW1A_HUMAN antibody FBXW1 antibody FBXW1A antibody FWD1 antibody HOS antibody mKIAA4123 antibody pIkappaBalpha-E3 receptor subunit antibody Slimb antibody
Abbreviation
BTRC
Swiss Prot
Q9Y297 Human, Q3ULA2 Mouse,
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Beta TRCP aa 1-200 / 605.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2 cell lysate, Hela cell lysate, 293T cell lysate, mouse testis tissue lysate, rat brain tissue lysate, mouse brain tissue lysate, A549, human colon tissue, mouse large intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IF-Cell: 1:100;IHC-P: 1:1,000-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 69 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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