Beta TRCP Rabbit Polyclonal Antibody
CAT:
992-HA500358
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Beta TRCP Rabbit Polyclonal Antibody
- Description: F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 residue structural motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a phosphorylation-dependent manner. F-box proteins are divided into 3 classes: Fbxws containing WD40 repeats; Fbxls containing leucine-rich repeats; Fbxos containing either "other" protein–protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxw class as, in addition to an F-box, this protein contains multiple WD40 repeats. This protein is homologous to Xenopus βTrCP, yeast Met30, Neurospora Scon2 and Drosophila Slimb. In mammals, in addition to βTrCP1, a paralog protein (called βTrCP2 or FBXW11) also exists, but, so far, their functions appear redundant and indistinguishable.
- Alternative Name: Beta transducin repeat containing E3 ubiquitin protein ligase antibody beta TrCP1 antibody beta-transducin repeat containing antibody BETA-TRCP antibody betaTrCP antibody btrC antibody bTrCP antibody bTrCP1 antibody E3RSIkappaB antibody F box and WD repeat protein 1B antibody F box and WD repeats protein beta TrCP antibody F-box and WD repeats protein beta-TrCP antibody F-box/WD repeat protein 1A antibody F-box/WD repeat-containing protein 1A antibody FBW1A antibody FBW1A_HUMAN antibody FBXW1 antibody FBXW1A antibody FWD1 antibody HOS antibody mKIAA4123 antibody pIkappaBalpha-E3 receptor subunit antibody Slimb antibody
- Abbreviation: BTRC
- Swiss Prot: Q9Y297 Human, Q3ULA2 Mouse,
- Cellular Locus: Cytoplasm, Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant protein within Human Beta TRCP aa 1-200 / 605.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IF-Cell, IHC-P
- Positive Control: HepG2 cell lysate, Hela cell lysate, 293T cell lysate, mouse testis tissue lysate, rat brain tissue lysate, mouse brain tissue lysate, A549, human colon tissue, mouse large intestine tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:1,000;IF-Cell: 1:100;IHC-P: 1:1,000-1:2,000
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 69 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No