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ERp72 Rabbit Polyclonal Antibody

CAT: 0992-R1409-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1409-1Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum in eukaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif. The reduced (that is, dithiol) form of PDI is able to catalyse a reduction of mispaired thiol residues of a particular substrate, acting as an isomerase. Another major function of PDI relates to its activity as a chaperone; i.e., it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI helps load antigenic peptides into MHC class I molecules. These molecules (MHC I) are related to the peptide presentation by antigen-presenting cells in the immune response.
CAS Number
9007-83-4
Product Name Alternative
Calcium binding protein intestinal related antibody Endoplasmic reticulum resident protein 70 antibody Endoplasmic reticulum resident protein 72 antibody EPR70 antibody EPR72 antibody ER protein 70 antibody ER protein 72 antibody ERP 70 antibody ERp 72 antibody ERp-72 antibody ERp70 antibody ERp72 antibody PDIA 4 antibody Pdia4 antibody PDIA4_HUMAN antibody PDIR antibody Protein disulfide isomerase A4 antibody Protein disulfide isomerase associated 4 antibody Protein disulfide isomerase family A member 4 antibody protein disulfide isomerase related protein (calcium-binding protein, intestinal-related) antibody Protein disulfide isomerase related protein antibody Protein disulfide-isomerase A4 antibody Protein ERp 72 antibody Protein ERp72 antibody
Abbreviation
ER protein 70,ERp70,ER protein 72,ERp-72,ERp72
Swiss Prot
P13667 Human, P08003 Mouse, P38659 Rat
Cellular Locus
Endoplasmic reticulum lumen, Melanosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminalhuman ERP72.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HeLa cell lysate, SK-Br-3 cell lysate, HepG2 cell lysate, PANC-1 cell lysate, PC-12 cell lysate, human liver tissue lysate, mouse liver tissue lysate, A549, PC-12, human lung cancer tissue.
Concentration
1 mg/mL
Dilution
WB:1:5,000 ;IF-Cell:1:500 ;IHC-P:1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 73 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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