GATA4 Rabbit Polyclonal Antibody

GATA4 Rabbit Polyclonal Antibody

• Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase.
• Product Name Alternative: ASD2 antibody GATA 4 antibody GATA binding protein 4 antibody GATA-binding factor 4 antibody gata4 antibody GATA4_HUMAN antibody MGC126629 antibody Transcription factor GATA 4 antibody Transcription factor GATA-4 antibody Transcription factor GATA4 antibody VSD1 antibody
• Abbreviation: GATA4
• CAS Number: 9007-83-4
• Swiss Prot: P43694 Human, Q08369 Mouse
• Cellular Locus: Nucleus
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within human GATA4 aa 280-430.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, FC
• Positive Control: HepG2, Jurkat, F9
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 45 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No