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GATA4 Rabbit Polyclonal Antibody

CAT: 0992-R1107-5Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1107-5Size:100 µL
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Description
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase.
CAS Number
9007-83-4
Product Name Alternative
ASD2 antibody GATA 4 antibody GATA binding protein 4 antibody GATA-binding factor 4 antibody gata4 antibody GATA4_HUMAN antibody MGC126629 antibody Transcription factor GATA 4 antibody Transcription factor GATA-4 antibody Transcription factor GATA4 antibody VSD1 antibody
Abbreviation
GATA4
Swiss Prot
P43694 Human, Q08369 Mouse
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human GATA4 aa 280-430.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
HepG2, Jurkat, F9
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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