GATA2 + GATA3 Recombinant Rabbit Monoclonal Antibody [JE04-46]

• Description:

  GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively. The gene and its product are targets for the treatment of these diseases. GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes.

• Product Name Alternative:

  DCML antibody Endothelial transcription factor GATA 2 antibody Endothelial transcription factor GATA-2 antibody GATA binding factor 3 antibody GATA binding protein 2 antibody GATA binding protein 3 antibody GATA-binding protein 2 antibody GATA-binding protein 3 antibody HDR antibody HDRS antibody IMD21 antibody MONOMAC antibody NFE1B antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans acting T cell specific transcription factor GATA-3 antibody

• Abbreviation:

  GATA2, GATA3

• Swiss Prot:

  P23769 Human, P23771 Human, O09100 Mouse, P23772 Mouse, Q924Y4 Rat

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within

• Isotype:

  IgG

• Clone:

  JE04-46

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P

• Positive Control:

  HeLa cell lysate, K-562 cell lysate, NIH/3T3 cell lysate, bEND.3 cell lysate, PC-12 cell lysate, human placenta tissue, human prostate cancer tissue, mouse kidney tissue, rat kidney tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IHC-P: 1:200-1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 51 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3