N-Cadherin Mouse Monoclonal Antibody [A10-4]

N-Cadherin Mouse Monoclonal Antibody [A10-4]

• Description: The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events. The cadherin subfamily includes N-, P-, B-, and E- cadherins, and other members. Recent studies indicate that cancer cells have up-regulated N-cadherin in addition to loss of E-cadherin. This change in cadherin expression is called the "cadherin switch". N-cadherin cooperates with the FGF receptor, leading to overexpression of MMP-9 and cellular invasion.
• Product Name Alternative: CADH2_HUMAN antibody Cadherin 2 antibody Cadherin 2 N cadherin neuronal antibody Cadherin 2 type 1 antibody Cadherin 2 type 1 N cadherin neuronal antibody Cadherin 2, type 1, N-cadherin (neuronal) antibody Cadherin-2 antibody Cadherin2 antibody Calcium dependent adhesion protein neuronal antibody CD325 antibody CD325 antigen antibody CDH2 antibody CDHN antibody CDw325 antibody CDw325 antigen antibody N cadherin 1 antibody N-cadherin antibody NCAD antibody Neural cadherin antibody OTTHUMP00000066304 antibody OTTHUMP00000067378 antibody
• Abbreviation: N-cadherin
• CAS Number: 9007-83-4
• Swiss Prot: P19022 Human
• Cellular Locus: Cell membrane.
• Host: Mouse
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein within Human N-Cadherin aa 401-600 / 906.
• Isotype: IgM
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Mouse heart tissue lysate, human heart tissue lysate.
• Concentration: 2 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:500 ;IHC-P: 1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 100 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No