Pan-Cadherin Recombinant Rabbit Monoclonal Antibody [ST54-01]

Pan-Cadherin Recombinant Rabbit Monoclonal Antibody [ST54-01]

• Description: Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH₂ terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin, R-cadherin, B-cadherin, E/P cadherin and cadherin-5.
• Product Name Alternative: Cadherin antibody CDH3 antibody CDHP antibody 7B4 antigen antibody Cadherin-1 antibody Cadherin-2 antibody Cadherin-3 antibody Cadherin-4 antibody Cadherin-5 antibody CAM 120/80 antibody CD144 antibody CD324 antibody CD325 antibody Cdh4 antibody CDH5 antibody CDHE antibody CDHN antibody E-cadherin antibody Epithelial cadherin antibody N-cadherin antibody NCAD antibody Neural cadherin antibody P-cadherin antibody Placental cadherin antibody UVO antibody Uvomorulin antibody Vascular endothelial cadherin antibody
• Abbreviation: E-cadherin, CDH1, CDHE, UVO, CDH2, CDHN, NCAD, P-cadherin, CDH3, CDHP, VE-cadherin, CDH5, R-CAD, R-cadherin
• CAS Number: 9000-83-3
• Swiss Prot: P19022 Human, P12830 Human, P22223 Human, P33151 Human, P55283 Human, P39038 Mouse
• Cellular Locus: Cell membrane, Cell junction, Endosome, Golgi apparatus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within C-terminal human CDH2.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC, IHC-Fr
• Positive Control: Human heart tissue lysate, mouse heart tissue lysate, rat heart tissue lysate, HeLa, Caco-2, mouse liver tissue, mouse kidney tissue, mouse heart tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:200 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration. ;IHC-Fr: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 100 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes