VE Cadherin Recombinant Rabbit Monoclonal Antibody [JJ0941]

VE Cadherin Recombinant Rabbit Monoclonal Antibody [JJ0941]

• Description: The cadherins are a family of Ca²⁺-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
• Product Name Alternative: 7B 4 antibody 7B4 antibody 7B4 antigen antibody CADH5_HUMAN antibody Cadherin 5 antibody Cadherin 5 type 2 antibody Cadherin 5, type 2 (vascular endothelium) antibody Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody cadherin, vascular endothelial antibody cadherin, vascular endothelial, 1 antibody Cadherin-5 antibody Cadherin5 antibody CD 144 antibody CD144 antibody CD144 antigen antibody CDH 5 antibody CDH5 antibody CDH5 protein antibody Endothelial specific cadherin antibody FLJ17376 antibody OTTHUMP00000174777 antibody Vascular endothelial cadherin antibody Vascular epithelium cadherin antibody VE Cad antibody VE-cadherin antibody VEC antibody
• Abbreviation: VE-cadherin, Cdh5
• CAS Number: 9000-83-3
• Swiss Prot: P55284 Mouse
• Cellular Locus: Cell junction, Cell membrane.
• Host: Rabbit
• Species Reactivity: Mouse
• Immunogen: Recombinant protein within mouse VE Cadherin aa 57-254 / 784.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP
• Positive Control: Mouse heart tissue lysate, mouse placenta tissue lysate, mouse spleen tissue lysate, mouse lung tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 88 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes