E-Cadherin Recombinant Mouse Monoclonal Antibody [A0-G11-2-R]

E-Cadherin Recombinant Mouse Monoclonal Antibody [A0-G11-2-R]

• Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
• Product Name Alternative: Cadherin-1 CAM 120/80 Epithelial cadherin (E-cadherin) Uvomorulin
• Abbreviation: CDH1
• CAS Number: 9000-83-3
• Swiss Prot: P12830 Human, P09803 Mouse, Q9R0T4 Rat
• Cellular Locus: Cell membrane, Endosome, Golgi apparatus.
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within mouse E-Cadherin aa 350-550.
• Isotype: IgG
• Clone: A0-G11-2-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, IHC, mIHC
• Positive Control: A431 cell lysate, SW480 cell lysate, MCF7 cell lysate, human breast carcinoma tissue, human liver cancer tissue, human liver tissue, human lung cancer tissue, rat kidney tissue.
• Concentration: 1mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IHC: 1:200-1:10,000 ;mIHC: 1:4,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 98 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes