K Cadherin Recombinant Rabbit Monoclonal Antibody [JE40-27]

K Cadherin Recombinant Rabbit Monoclonal Antibody [JE40-27]

• Description: Cadherin-6 is a protein that in humans is encoded by the CDH6 gene. This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell–cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
• Product Name Alternative: CAD6 antibody CADH6_HUMAN antibody Cadherin 6 antibody Cadherin 6 type 2 antibody Cadherin 6 type 2 K cadherin (fetal kidney) antibody Cadherin fetal kidney antibody Cadherin-6 antibody Cadherin6 antibody CDH 6 antibody Cdh6 antibody K-cadherin antibody KCAD antibody Kidney cadherin antibody
• Abbreviation: CDH6
• CAS Number: 9000-83-3
• Swiss Prot: P55285 Human, P97326 Mouse, P55280 Rat
• Cellular Locus: Cell membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human K Cadherin/CDH6 aa 750-790.
• Isotype: IgG
• Clone: JE40-27
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Tissue
• Positive Control: Jurkat cell lysate, A549 cell lysate, 293T cell lysate, HepG2 cell lysate, human kidney tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, human kidney tissue, mouse kidney tissue, rat kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000 ;IHC-P: 1:5,000-1:10,000 ;IF-Tissue: 1:500-1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 88 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes