Phospho-MCM2 (S108) Recombinant Rabbit Monoclonal Antibody [JE63-52]

Phospho-MCM2 (S108) Recombinant Rabbit Monoclonal Antibody [JE63-52]

• Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
• Product Name Alternative: BM28 antibody CCNL 1 antibody CCNL1 antibody CDC like 1 antibody cdc19 antibody CDCL 1 antibody CDCL1 antibody Cell devision cycle like 1 antibody Cyclin like 1 antibody D3S3194 antibody DNA replication licensing factor MCM2 antibody KIAA0030 antibody MCM 2 antibody MCM2 antibody MCM2 minichromosome maintenance deficient 2 mitotin antibody MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody MCM2 minichromosome maintenance deficient 2, mitotin antibody MCM2_HUMAN antibody MGC10606 antibody Minichromosome maintenance complex component 2 antibody Minichromosome maintenance deficient 2 (mitotin) antibody Minichromosome maintenance deficient 2 mitotin antibody Minichromosome maintenance protein 2 antibody Minichromosome maintenance protein 2 homolog antibody Mitotin antibody Nuclear protein BM28 antibody OTTHUMP00000216047 antibody OTTHUMP00000216050 antibody
• Abbreviation: MCM2
• CAS Number: 9000-83-3
• Swiss Prot: P49736 Human, P97310 Mouse,
• Cellular Locus: Nucleus, Chromosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within corresponding to residues surrounding ser108 of Human MCM2.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: SiHa cell lysates, HL-60 cell lysates, rat large intestine tissue, human lymph node tissue, human small intestine tissue, mouse testis tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:400
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 102 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes