Glucosidase 2 subunit beta Mouse Monoclonal Antibody [A6H9]

Glucosidase 2 subunit beta Mouse Monoclonal Antibody [A6H9]

• Description: Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc (2)Man (9)GlcNAc (2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.
• Product Name Alternative: 80K-H protein antibody AGE-binding receptor 2 antibody AGE-R2 antibody G19P1 antibody GLU2B_HUMAN antibody Glucosidase 2 subunit beta antibody Glucosidase II beta subunit antibody Glucosidase II subunit beta antibody Hepatocystin antibody PCLD antibody PKCSH antibody PLD1 antibody PRKCSH antibody Protein kinase C substrate 60.1 kDa protein heavy chain antibody Protein kinase C substrate 80 Kda protein antibody Protein kinase C substrate 80K-H antibody Protein kinase C substrate, 80 Kda protein antibody
• Abbreviation: PRKCSH
• CAS Number: 9007-83-4
• Swiss Prot: P14314 Human
• Cellular Locus: Endoplasmic reticulum.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant protein within human Glucosidase 2 subunit beta aa 51-250.
• Isotype: IgG1
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: HeLa cell lysate, 293T cell lysate, Daudi cell lysate, Jurkat cell lysate, A431 cell lysate, Hela, human placenta tissue.
• Concentration: 2 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200 ;FC: 1:500-1:1,000
• Purity: Protein G affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 59 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No